Experimental Proteomics and Biochemical Characterization of de novo peptides
Type d'annonce : Offre d'emploi CDD IE/IR
De : Unité de Glycobiologie Structurale et Fonctionnelle , Villeneuve d'Ascq / Lille University - site internet
A fixed-term position for a Research Engineer (IR) is available in Lille (France) within the interdisciplinary PIE project (“Protein Interactions and Evolution”), funded by the Excellence Initiative of the Université de Lille (https://initiative-excellence.univlille.fr/en/our-structural-projects/pursue-research-excellence/cross-disciplinary-projects/pie-cdp). The PIE project investigates how novel protein interactions emerge during evolution, and how evolutionary changes in protein interactions drive speciation and major innovations in molecular, metabolic, and morphological traits through co-evolutionary processes.
Work package 1 of the project focuses on the emergence of de novo peptides and proteins, i.e. encoded by genes arising from previously non-coding genomic regions, and their integration into cellular regulatory networks. While many newly emerged peptides may be transient and evolve neutrally, some appear capable of acquiring new functions and participating in major evolutionary innovations. Using closely related species from the model genus Arabidopsis, the project combines comparative genomics, proteomics, structural biology and computational modeling to identify recently emerged peptides and characterize their biochemical properties and interaction partners.
Détails de l'annonce
- Profil : Required qualifications and skills: • PhD or equivalent qualification in biochemistry, biophysics, or related fields • Ability to work autonomously while interacting efficiently within a multidisciplinary research environment, good communication skills in English. • Strong experimental background in biochemistry and/or proteomics, • Strong experience with mass spectrometry, The following skills would be considered advantageous: • Experience with cross-linking MS, • Experience with biophysical interaction methods, • Interest in molecular evolution and emerging proteins.
- Durée de contrat : 18 months
- Date de prise de fonction : Autumn 2026
- Documents à fournir pour candidater : CV, Lettre de motivation, Lettre de recommandation
- Date limite de candidature : 15/07/2026
Personne à contacter
- Nom : julie.bouckaert@univ-lille.fr
- Téléphone : +33320531729
- Email : julie.bouckaert@univ-lille.fr