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Development and application of advanced cell-free protein synthesis for the NMR study of large macromolecular systems

Type d'annonce : Offre de thèse

De : Institut de biologie physico-chimique , Paris - site internet

A PhD position is available in the team Biogenesis, architecture and interactions of RNA led by Dr. Tisné, at the Institut de biologie physico-chimique (IBPC) in Paris, France. The successful candidate will work on the development of tRNA production for innovative cell-free protein synthesis, and on the application of these innovative isotope labeling methods to relevant protein/RNA complexes. The position is funded by the European Research Council under the Advanced Grant project XXL-NMR. The successful candidate will work under the co-supervision of Dr. Barraud (IBPC, Paris) and Dr. Boisbouvier (IBS, Grenoble).

Facilities: The IBPC, a historic multidisciplinary institute embedded in a dense research campus, offers interaction with many experts in the field of molecular biology and at the interface with physics, chemistry and computational biology. The IBPC offers a vibrant international working environment with state-of-the-art platforms including crystallography, biophysics, NMR, mass spectrometry, data visualisation and functional genomics. The IBPC is located in the centre of Paris, in the Latin Quarter, a dynamic student area, close to historical monuments and public transport.

Qualification: Candidates should hold a Master degree in biology, biochemistry, biophysics, or structural biology. Expertise or interest in the development of isotope labeling methods will be highly appreciated. Interested candidates should send a CV, a covering letter and the names and email addresses of two referees. These documents should be submitted by email to pierre.barraud@ibpc.fr and jerome.boisbouvier@ibs.fr

Détails de l'annonce

  • Durée de contrat : 3 years
  • Date de prise de fonction : 01/10/2024
  • Documents à fournir pour candidater : CV, Lettre de motivation
  • Date limite de candidature : 23/06/2024

Personne à contacter

  • Nom : Pierre Barraud
  • Email : pierre.barraud@ibpc.fr